Knockout of the DAS gene increases S-adenosylmethionine production in Komagataella phaffii
S-adenosylmethionine (SAM) is an important compound in living organisms and has a number of different roles, such as polyamine synthesis.It can also be used for the treatment vitamin c serum of diseases.Gene targeting with homologous recombination in Komagataella phaffii (K.phaffii) created DAS1 and DAS2 gene knockout strains, which use the methano